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Snake

Research

On-going

  1. Computational and experimental discovery of new biotherapeutics against cytotoxin.

  2. Discovery of aptamer as toxin-neutralisation molecule.

  3. Environmental toxin monitoring toolkit.

  4. Repurposing venom-derived peptides as combatants against antibiotic resistance. 

  5. Epitope characterisation and mapping of venom cytotoxin to develop next-generation toxin targeted biotherapeutics.

  6. Pharmacophore-based design of cationic cell-penetrating peptides derived from cytotoxin as antimicrobial molecules.

  7. Pharmacophore modelling based inhibitor selection of cytotoxin towards the discovery of novel therapeutics for dermonecrosis. 

  8. Next-generation aptamer-based biotherapeutics as antivenom and antimicrobial agent in envenomation. 

Completed

  1. MELD-mass spectrometry approach in functional epitope mapping of cobra venom cytotoxin.

  2. Experimental and computational approach to reveal the fundamental insights into the mechanisms of cytotoxicity for cobra cytotoxins.

  3. Unravelling the mechanisms of cytotoxin-induced transition of cell death pattern using proteomics approach. 

  4. IoT and Industry 4.0: A rapid tool to bio-prospect microalgae with wound healing properties. 

  5. Technology Surveillance of Microalgae Blooms at Freshwater: The Next-generation Discovery of Sustainable Resources.

  6. Purification, gene cloning, and expression of cytotoxin in mammalian expression vectors. 

Bioinformatics and computational research

  • Ensemble-based virtual screening of death receptors with cytotoxin using molecular dynamic and molecular docking

  • Physicochemical and domain architecture of cytotoxin.

  • Molecular dynamic simulation of cytotoxin with membrane.

  • Immunoinformatics analysis.  

  • High-throughput virtual screening (HTVS) and pharmacophore modeling 

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Monash University Malaysia, Jalan Lagoon Selatan, 47500 Bandar Sunway, Malaysia.

603-5514 5860

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